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Anti-ADAR1 Antibody

Affinity purified rabbit polyclonal antibody to detect expression of Double-stranded RNA-specific adenosine deaminase in human, mouse, rat and porcine samples
Catalog #: A2035
$325.00

Product Details

Size 100 µl
Antibody Target ADAR1
Alternate Name ADAR1; DSRAD; G1P1; IFI4; Double-stranded RNA-specific adenosine deaminase; DRADA; 136 kDa double-stranded RNA-binding protein; p136; Interferon-inducible protein 4; IFI-4; K88DSRBP
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Immunogen KLH-conjugated synthetic peptide targeting a sequence within the C-term region of human ADAR1
Accession # P55265
Gene ID 103
Appearance Colorless liquid
Formulation In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide
Purification Affinity purified
Species Reactivity Porcine, Rat, Mouse, Human
Application Immunohistochemistry (IHC), Western Blotting
Application & Usage WB 1:500 - 1:1000, IHC 1:100 - 1:200
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Double-stranded RNA-specific adenosine deaminase (ADAR1) encodes the enzyme that is responsible for destabilization of double-stranded RNA by deaminating adenosine to inosine in non-coding repetitive elements and short interspersed nuclear elements. ADAR1 is known to be expressed in embryonic cells and adult tissues and is responsible for the maturation and differentiation of these cells and tissues. ADAR1 also plays an essential role in the maintenance of hematopoietic stem cells. Several isoforms of ADAR1 exist, which includes a full-length protein (150 kDa) and two short functionally active isoforms (80 and 110 kDa).


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