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Anti-ACE2 Antibody

Rabbit polyclonal antibody to detect ACE2 expression in human samples
Catalog #: A2072
$340.00

Product Details

Cat # +Size A2072-100
Size 100 μg
Antibody Target ACE2
Alternate Name Angiotensin-converting enzyme 2; ACE-related carboxypeptidase; Angiotensin-converting enzyme homolog; ACEH; Metalloprotease MPROT15
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Immunogen Recombinant Human Angiotensin-converting enzyme 2 protein (395-638 aa)
Accession # Q9BYF1
Gene ID 59272
Appearance Colorless liquid
Formulation In 0.01 M PBS, pH 7.4, 50% Glycerol, 0.03% proclin 300
Purification Affinity purified
Species Reactivity Human
Application Immunofluorescence (IF), Immunohistochemistry (IHC)
Application & Usage IHC 1:20-1:200, IF 1:50-1:200
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronavirus HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2 (COVID-19 virus)


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