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Annexin V, human recombinant

based on 10 citations in multiple journalsAnnexin V, human recombinant104.2 4
A reagent for detecting early stages of apoptosis
Catalog #: 1005
SKU-Size Size Price Qty
1005-100 100 μg
$250.00
1005-1000 1 mg
$1,825.00
1005-5000 5 mg
$5,245.00
More Sizes Get Quote

Product Details

Alternate Name Anchorin CII, Annexin V, Annexin-5, Calphobindin I, Endonexin II, Lipocortin V, Placental anticoagulant protein 4, lacental anticoagulant protein I, Thromboplastin inhibitor, Vascular anticoagulant-alpha, PP4, ANX5, ENX2, ANXA5, Annexin A5, Annexin-5, Ann
Source E.coli
Appearance Lyophilized
Purity by SDS-PAGE ≥98%
Reconstitution Instructions Reconstitute the lyophilized forms with H₂O or PBS to a final concentration of 1-5 mg/ml.
Handling Centrifuge the vial prior to opening.
Storage Conditions 4°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Reagent for detecting early stages of apoptosis. During apoptosis, phosphatidylserine (PS) is translocated from the cytoplasmic face of the plasma membrane to the cell surface. Annexin V has a strong, Ca2+-dependent affinity for PS and therefore is used as a probe for detecting apoptosis. The unlabeled Annexin V reagent can be conjugated to any tag of choice for detection of apoptosis. The reagent can also be used in competition binding experiments to compete with tagged annexin V conjugates. Annexin V-FITC, -Cy3, -Cy5, -EGFP, -PE, PE/CY5, and -Biotin Labels are also available separately.


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Gregory R. Bean et al., PUMA and BIM Are Required for Oncogene Inactivation–Induced Apoptosis. Sci. Signal., Mar 2013; 6: ra20.
Galvan, M.  et al Complement Component C1q Regulates Macrophage Expression of Mer Tyrosine Kinase To Promote Clearance of Apoptotic Cells,  J. Immunol., Apr 2012; 188: 3716 - 3723.
Tanaka, A. et al. Hyperoxia-Induced LC3B Interacts with the Fas Apoptotic Pathway in Epithelial Cell Death, Am. J. Respir. Cell Mol. Biol., Apr 2012; 46: 507 - 514.
Fens, M. et al. A role for activated endothelial cells in red blood cell clearance: implications for vasopathology Haematologica, Apr 2012; 97: 500 - 508.
Mirza, H. et. al. A Rapid, High-Throughput Viability Assay for Blastocystis spp. Reveals Metronidazole Resistance and Extensive Subtype-Dependent Variations in Drug Susceptibilities. Antimicrob. Agents Chemother., Feb 2011; 55: 637 - 648.
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