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Annexin V-EGFP Reagent

based on 8 citations in multiple journalsAnnexin V-EGFP Reagent84.1 4
EGFP conjugated Annexin V for detection of apoptosis through fluorescence microscopy or by flow cytometry
Catalog #: 1004
SKU-Size Size Price Qty
1004-200 200 assays
$325.00
1004-1000 1000 assays
$995.00
More Sizes Get Quote

Product Details

Highlights • Detection method- flow cytometry (Ex/ Em- 488 /530 nm) using FITC signal detector (usually FL1) and fluorescence microscopy
• Sample- Cell culture
• Simple, easy to use and convenient
Storage Conditions 4°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The bright and photo-stable reagent for detecting early stages of apoptosis. During apoptosis, phosphatidylserine (PS) is translocated from the cytoplasmic face of the plasma membrane to the cell surface. Annexin V has a strong, Ca²ᶧ -dependent affinity for PS and therefore serves as a probe for detecting apoptosis. The annexin V-EGFP fusion is brighter and photo-stable, ideal for detecting apoptosis by fluorescence microscopy with a FITC filter or by flow cytometry.


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Joel D. Schilling et al., TLR4 Activation Under Lipotoxic Conditions Leads to Synergistic Macrophage Cell Death through a TRIF-Dependent Pathway. J. Immunol., Feb 2013; 190: 1285 - 1296.
Urte Neniskyte, et. al. Neuronal Death Induced by Nanomolar Amyloid β Is Mediated by Primary Phagocytosis of Neurons by Microglia. J. Biol. Chem., Nov 2011; 286: 39904 - 39913.
Kuhn DJ et al (2009) Blood; 113: 4667 - 4676.
Campbell RA., et al. (2001) J. Biol. Chem. 276:9817-9824.
Goldberg, G.S., et al. (2001) Cancer Res. 61:1334-1337.
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