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Angiostatin Human

An endogenous angiogenesis inhibitor 
Catalog #: 4919
SKU-Size Size Price Qty
4919-100 100 μg
$205.00
4919-500 500 μg
$730.00
More Sizes Get Quote

Product Details

Alternate Name Angiostatin K1-4, Angiostatin Kringles 1-4, plasminogen
Source Human Plasma
Appearance Liquid
Physical Form Description In 20 mM HEPES, 150 mM NaCl, pH 7.4
Molecular Weight 50.0 kDa
Purity by SDS-PAGE ≥95%
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans

Details

Angiostatin is a proteolytic fragment of plasminogen constituting kringles 1 - 4. It is a potent angiogenesis inhibitor and the inhibition of angiogenesis by angiostatin is directly related to inhibiting the proliferation of endothelial cells. Human Angiostatin significantly inhibits bFGF-induced endothelial cell proliferation and migration at concentrations ranging from 300 nM – 1.0 µM.


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