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Anagrelide

A phosphodiesterase 3 (PDE3) Inhibitor
Catalog #: B2446
SKU-Size Size Price Qty
B2446-5 5 mg
$115.00
B2446-25 25 mg
$455.00
More Sizes Get Quote

Product Details

Alternate Name 6,7-dichloro-5,10-dihydro-3H-imidazo[2,1-b]quinazolin-2-one, BL 4162A, Agrelin, Thromboreductin
Appearance Crystalline solid
CAS # 68475-42-3
Molecular Formula C₁₀H₇Cl₂N₃O
Molecular Weight 256.09
Purity ≥98%
Solubility in DMSO
SMILES C1C2=C(C=CC(=C2Cl)Cl)N=C3N1CC(=O)N3
InChi InChI=1S/C10H7Cl2N3O/c11-6-1-2-7-5(9(6)12)3-15-4-8(16)14-10(15)13-7/h1-2H,3-4H2,(H,13,14,16)
InChi Key OTBXOEAOVRKTNQ-UHFFFAOYSA-N
PubChem CID 135409400
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Anagrelide is a phosphodiesterase 3 (PDE3) inhibitor (IC₅₀ = 36 nM) with antiplatelet activity. Anagrelide inhibits the maturation of megakaryocytes into platelets, reducing both megakaryocyte hyperproliferation and differentiation. Anagrelide is used for the treatment of overproduction of blood platelets.


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