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A phosphodiesterase 3 (PDE3) inhibitor
Catalog #: B2465
SKU-Size Size Price Qty
B2465-50 50 mg
B2465-250 250 mg
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Product Details

Alternate Name 5-amino-[3,4'-bipyridin]-6(1H)-one; WIN 40,680
Appearance Beige to yellow solid
CAS # 60719-84-8
Molecular Formula C₁₀H₉N₃O
Molecular Weight 187.2
Purity ≥98% by HPLC
Solubility 0.5 mg/ml DMSO
InChi InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14)
PubChem CID 3698
MDL Number MFCD00083228
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Amrinone is a potent phosphodiesterase 3 (PDE3) inhibitor (IC₅₀ = 19.5 µM). It increases developed tension and contractile force in isolated cat papillary muscle. It also displays positive inotropic effects, increasing the rate and force of heart contraction in anesthetized and unanesthetized dogs.

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