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AMPK Activator, D942

A potent AMPK activator
Catalog #: 2341
SKU-Size Size Price Qty
2341-1 1 mg
$60.00
2341-5 5 mg
$205.00
More Sizes Get Quote

Product Details

Alternate Name 5-(3-(4-(2-(4-Fluorophenyl)ethoxy)phenyl)propyl)furan-2-carboxylic acid
Appearance Light yellow solid
CAS # 849727-81-7
Molecular Formula C₂₂H₂₁FO₄
Molecular Weight 368.4
Purity ≥98% by HPLC
Solubility DMSO (10 mg/ml)
SMILES C1=CC(=CC=C1CCCC2=CC=C(O2)C(=O)O)OCCC3=CC=C(C=C3)F
InChi InChI=1S/C22H21FO4/c23-18-8-4-17(5-9-18)14-15-26-19-10-6-16(7-11-19)2-1-3-20-12-13-21(27-20)22(24)25/h4-13H,1-3,14-15H2,(H,24,25)
InChi Key MPLLLQUZNJSVTK-UHFFFAOYSA-N
PubChem CID 16760291
Handling Protect from air and light
Storage Conditions -20 ̊C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Cell-permeable. A potent activator of AMPK (AMP-activated protein kinase). The activation of AMPK was achieved through inhibition of NAD(P)H dehydrogenase [quinone] 1 (complex I). D942 increases glucose uptake in L6 myocytes, and inhibits CCL2-induced mTORC1 activity and survivin expression in human prostate cancer PC-3 cells.


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