Product Details
| Alternate Name | 5-(3-(4-(2-(4-Fluorophenyl)ethoxy)phenyl)propyl)furan-2-carboxylic acid |
|---|---|
| Appearance | Light yellow solid |
| CAS # | 849727-81-7 |
| Molecular Formula | C₂₂H₂₁FO₄ |
| Molecular Weight | 368.4 |
| Purity | ≥98% by HPLC |
| Solubility | DMSO (10 mg/ml) |
| SMILES | C1=CC(=CC=C1CCCC2=CC=C(O2)C(=O)O)OCCC3=CC=C(C=C3)F |
| InChi | InChI=1S/C22H21FO4/c23-18-8-4-17(5-9-18)14-15-26-19-10-6-16(7-11-19)2-1-3-20-12-13-21(27-20)22(24)25/h4-13H,1-3,14-15H2,(H,24,25) |
| InChi Key | MPLLLQUZNJSVTK-UHFFFAOYSA-N |
| PubChem CID | 16760291 |
| Handling | Protect from air and light |
| Storage Conditions | -20 ̊C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Cell-permeable. A potent activator of AMPK (AMP-activated protein kinase). The activation of AMPK was achieved through inhibition of NAD(P)H dehydrogenase [quinone] 1 (complex I). D942 increases glucose uptake in L6 myocytes, and inhibits CCL2-induced mTORC1 activity and survivin expression in human prostate cancer PC-3 cells.
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