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AMPK⍺1 Antibody

Catalog #: 3110

In stock

$325.00

Product Details

Cat # +Size 3110-100
Size 100 µg
Antibody Target AMPK⍺1
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide selected from the C-terminal region of human AMPK alpha 1
Accession # Q13131
Gene ID 5562
Appearance Colorless liquid
Concentration 0.25 mg/ml
Formulation 100 µg (0.25 mg/ml) purified rabbit Ig polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification Affinity purified
Species Reactivity Human, mouse
Application ELISA, Western blot
Application & Usage The antibody can be used for ELISA (0.25 µg/ml) and Western blotting (0.5 – 2.5 µg/ml).
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. It appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. AMPK alpha1, a member of the Ser/Thr protein kinase family, is a catalytic subunit of AMPK.


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