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Amphotericin B, USP

An antibiotic and selection agent
Catalog #: 2497
SKU-Size Size Price Qty
2497-250 250 mg
$95.00
2497-1G 1 g
$295.00
2497-5G 5 g
$995.00
More Sizes Get Quote

Product Details

Alternate Name Fungizone
Appearance Yellow or orange powder
CAS # 1397-89-3
Molecular Formula C₄₇H₇₃NO₁₇
Molecular Weight 924.08
Purity >750 µg/mg
Solubility DMF (~2-4 mg/ml) or DMSO (~30-40 mg/ml)
SMILES CC1C=CC=CC=CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC(C(CCC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)O)OC3C(C(C(C(O3)C)O)N)O
InChi InChI=1S/C47H73NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56/h5-18,27-38,40-44,46,49-54,56-58,61H,19-26,48H2,1-4H3,(H,59,60)/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31+,32+,33-,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1
InChi Key APKFDSVGJQXUKY-INPOYWNPSA-N
PubChem CID 5280965
MDL Number MFCD00877763
Handling Protect from air and moisture
Storage Conditions 4°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A polyene antifungal antibiotic from Streptomyces. Amphotericin B targets a wide range of susceptible fungi including Histoplasma, Coccidioides, and Cryptococcus species. Amphotericin B targets ergosterol in the fungal cell membrane and increases permeability. This alteration of the cell membrane is toxic to the fungus and leads to death. Can be used as a selective agent in several types of isolation media.


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