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Amlexanox

An anti-allergy, anti-asthma and anti-diabetic agent
Catalog #: 2336
SKU-Size Size Price Qty
2336-10 10 mg
$75.00
2336-50 50 mg
$295.00
More Sizes Get Quote

Product Details

Alternate Name 2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid ; AA 673; Amoxanox, CHX 3673
Appearance White solid
CAS # 68302-57-8
Molecular Formula C₁₆H₁₄N₂O₄
Molecular Weight 298.29
Purity ≥98% by TLC
Solubility DMSO (60 mg/ml)
SMILES CC(C)C1=CC2=C(C=C1)OC3=NC(=C(C=C3C2=O)C(=O)O)N
InChi InChI=1S/C16H14N2O4/c1-7(2)8-3-4-12-9(5-8)13(19)10-6-11(16(20)21)14(17)18-15(10)22-12/h3-7H,1-2H3,(H2,17,18)(H,20,21)
InChi Key SGRYPYWGNKJSDL-UHFFFAOYSA-N
PubChem CID 2161
MDL Number MFCD00864790
Handling Protect from air and light
Storage Conditions -20 ̊C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

An anti-allergy, anti-asthma and anti-diabetic agent. Improves obesity-related metabolic dysfunction in mouse models. Increases thermogenesis and weight loss, decreases steatosis and improves insulin sensitivity. Inhibits TANK-binding kinase 1 (TBK1) and IKKe (IC₅₀ =1.2 µM). Clinically useful in treatment of aphthus ulcers.


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