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Aminopurvalanol A

A CDK inhibitor
Catalog #: 2205

In stock

SKU-Size Size Price Qty
2205-1 1 mg
$60.00
2205-5 5 mg
$230.00
More Sizes Get Quote

Product Details

Alternate Name (2R)-2-[[6-[(3-Amino-5-chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol; NG97
Appearance Pale yellow solid
CAS # 220792-57-4
Molecular Formula C₁₉H₂₆ClN₇O
Molecular Weight 403.91
Purity ≥98% by HPLC
Solubility DMSO (100 mM)
SMILES CC(C)C(CO)NC1=NC2=C(C(=N1)NC3=CC(=CC(=C3)N)Cl)N=CN2C(C)C
InChi InChI=1S/C19H26ClN7O/c1-10(2)15(8-28)24-19-25-17(23-14-6-12(20)5-13(21)7-14)16-18(26-19)27(9-22-16)11(3)4/h5-7,9-11,15,28H,8,21H2,1-4H3,(H2,23,24,25,26)/t15-/m0/s1
InChi Key RAMROQQYRRQPDL-HNNXBMFYSA-N
PubChem CID 6604931
MDL Number MFCD06798384
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A cell-permeable, reversible and competitive inhibitor of cyclin-dependent kinases. IC₅₀ values are: CDK1/cyclin B (33 nM), CDK2/cyclin A (33 nM), CDK2/cyclin E (28 nM) and CDK5/p35 (20 nM).


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