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AMG319 

 A highly selective inhibitor of phosphoinositide 3-kinase p110δ isoform 
Catalog #: B1663

In stock

SKU-Size Size Price Qty
B1663-5 5 mg
$95.00
B1663-25 25 mg
$375.00

Product Details

Alternate Name AMG319, AMG319; AMG 319; N-[(1S)-1-(7-fluoro-2-pyridin-2-ylquinolin-3-yl)ethyl]-7H-purin-6-amine; (S)-N-(1-(7-fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine
Appearance Solid
CAS # 1608125-21-8
Molecular Formula C₂₁H₁₆FN₇
Molecular Weight 385.4
Purity >98%
Solubility DMSO
SMILES CC(C1=C(N=C2C=C(C=CC2=C1)F)C3=CC=CC=N3)NC4=NC=NC5=C4NC=N5
InChi InChI=1S/C21H16FN7/c1-12(28-21-19-20(25-10-24-19)26-11-27-21)15-8-13-5-6-14(22)9-17(13)29-18(15)16-4-2-3-7-23-16/h2-12H,1H3,(H2,24,25,26,27,28)/t12-/m0/s1
InChi Key KWRYMZHCQIOOEB-LBPRGKRZSA-N
PubChem CID 68947304
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, also inhibits PI3Kγ with IC50 of 850 nM.


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