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Alvelestat

A oral inhibitor of neutrophil elastase
Catalog #: B1653
SKU-Size Size Price Qty
B1653-5 5 mg
$90.00
B1653-25 25 mg
$355.00
More Sizes Get Quote

Product Details

Alternate Name Alvelestat; AZD9668; AZD 9668; AZD-9668; 6-methyl-5-(1-methyl-1H-pyrazol-5-yl)-N-((5-(methylsulfonyl)pyridin-2-yl)methyl)-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2-dihydropyridine-3-carboxamide
Appearance Solid
CAS # 848141-11-7
Molecular Formula C₂₅H₂₂F₃N₅O₄S
Molecular Weight 543.53
Purity >98%
Solubility DMSO
SMILES CC1=C(C=C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)C(=O)NCC3=NC=C(C=C3)S(=O)(=O)C)C4=CC=NN4C
InChi InChI=1S/C25H22F3N5O4S/c1-15-20(22-9-10-31-32(22)2)12-21(23(34)30-13-17-7-8-19(14-29-17)38(3,36)37)24(35)33(15)18-6-4-5-16(11-18)25(26,27)28/h4-12,14H,13H2,1-3H3,(H,30,34)
InChi Key QNQZWEGMKJBHEM-UHFFFAOYSA-N
PubChem CID 46861623
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Alvelestat (AZD9668) is a novel, oral inhibitor of neutrophil elastase (NE) with the pIC50 of 7.9 for Human NE.


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