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alpha-Fodrin Antibody

Catalog #: 3266
SKU-Size Size Price Qty
3266-30T 30 µg
$89.00
3266-100 100 µg
$245.00
More Sizes Get Quote

Product Details

Antibody Target Fodrin
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide surrounding amino acid 162 of mouse alpha-Fodrin
Accession # P16546
Gene ID 20740
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation In phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin
Purification Affinity purified
Species Reactivity Human
Application Western blot, Immunohistochemistry
Application & Usage Western blot analysis (0.5-4 µg/ml) and in in Immunohistochemistry (10-20 µg/ml).
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Fodrin is a universally expressed membrane-associated cytoskeletal protein consisting of α- and β-subunits. The protein is important for maintaining normal membrane structure and supporting cell surface protein function. α-Fodrin is one of the important targets cleaved by caspases during apoptosis. The full length 240 kDa protein can be cleaved at several sites within its sequence by activated caspases generating N-terminal 150 kDa, C-terminal 120 kDa, and 35 kDa major products. Cleavage of α-Fodrin leads to membrane malfunction and cell shrinkage.


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