Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

Alpha 1 Antichymotrypsin, Human Plasma

An acute-phase plasma protein
Catalog #: 7293
$100.00

Product Details

Cat # +Size 7293-100
Size 100 μg
Alternate Name Cell growth-inhibiting gene 24/25 protein, Serpin A3, SERPINA3, AACT, GIG24, GIG25
Gene Symbol SERPINA3
Gene ID 12
Accession # P01011
Source Human Plasma
Appearance Lyophilized
Physical Form Description Lyophilized from 20 mM Tris-HCl, pH 7.4, with 150 mM NaCl.
Molecular Weight 64 kDa
Purity by SDS-PAGE ≥95%
Biological Activity Shows 75-100% inhibition when tested with active-site titrated porcine pancreatic trypsin using Na-Benzoyl-L-Arginine-para-Nitroanilide Hydrochloride (L-BAPNA) as substrate.
Reconstitution Instructions In water or aqueous buffer
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Alpha 1 antichymotrypsin is an acute-phase plasma protein found at 45 mg per 100 ml. ACT functions as a specific inhibitor of chymotrypsin-like serine proteases. Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. Clinically, it is elevated in inflammatory conditions, some malignancies, Crohn's disease, ulcerative colitis, and burn injuries. The PSA-ACT complex level is considered a biomarker for prostate cancer. Defects in this gene may be a cause of chronic obstructive pulmonary disease.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.