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Alogliptin benzoate

A potent, selective DPP-4 (dipeptidyl peptidase-4) inhibitor
Catalog #: 9656
SKU-Size Size Price Qty
9656-50 50 mg
$85.00
9656-250 250 mg
$335.00
More Sizes Get Quote

Product Details

Alternate Name 2-[[6-[(3R)-3-Amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]benzonitrile benzoate; SYR-322, Nesina, SYR322
Appearance White to off-white solid
CAS # 850649-62-6
Molecular Formula C₁₈H₂₁N₅O₂.C₇H₆O₂
Molecular Weight 461.52
Purity ≥98% by HPLC
Solubility DMSO (>10 mg/ml)
SMILES CN1C(=O)C=C(N(C1=O)CC2=CC=CC=C2C#N)N3CCCC(C3)N.C1=CC=C(C=C1)C(=O)O
InChi InChI=1S/C18H21N5O2.C7H6O2/c1-21-17(24)9-16(22-8-4-7-15(20)12-22)23(18(21)25)
InChi Key KEJICOXJTRHYAK-XFULWGLBSA-N
PubChem CID 16088021
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Alogliptin benzoate is a potent, selective inhibitor of DPP-4 (dipeptidyl peptidase-4) with an IC₅₀ of <10 nM. Displays greater than 10,000-fold selectivity over DPP-8 and DPP-9. An anti-diabetic agent for treatment of type 2 diabetes.


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