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ALK antibody

Catalog #: 3355
SKU-Size Size Price Qty
3355-30T 30 µg
$89.00
3355-100 100 µg
$245.00
More Sizes Get Quote

Product Details

Antibody Target ALK
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide corresponding to C-terminus of human ALK
Accession # Q9UM73
Gene ID 238
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 µg (0.5 mg/ml) rabbit anti-ALK polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification Affinity purified
Species Reactivity Human
Application Western blot
Positive Control Jurkat cell lysate
Application & Usage Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

ALK (anaplastic lymphoma kinase) was originally discovered as a NPM (Nucleophosmin)-ALK fusion protein. The NPM-ALK is a constitutively active oncogenic tyrosine kinase associated with anaplastic lymphoma. Activation of PLCgamma by NPM-ALK has been sμggested as a crucial step for this lymphoma-associated oncogenic tyrosine kinase.


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