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Alendronate sodium

A specific inhibitor of osteoclast-mediated bone resorption
Catalog #: 2168
SKU-Size Size Price Qty
2168-50 50 mg
2168-250 250 mg
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Product Details

Alternate Name Sodium [4-amino-1-hydroxy-1-(hydroxy-oxido-phosphoryl)- butyl]phosphonic acid, trihydrate; MK-217; Fosamax
Appearance White solid
CAS # 121268-17-5
Molecular Formula C₄H₁₂NaNO₇P₂ · 3 H₂O
Molecular Weight 325.12
Purity ≥95%
Solubility H₂O (10 mg/ml)
SMILES C(CC(O)(P(=O)(O)O)P(=O)(O)[O-])CN.O.O.O.[Na+]
InChi InChI=1S/C4H13NO7P2.Na.3H2O/c5-3-1-2-4(6,13(7,8)9)14(10,11)12;;;;/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12);;3*1H2/q;+1;;;/p-1
PubChem CID 23681107
MDL Number MFCD01748233
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Alendronate sodium is a bisphosphonate that acts as a specific inhibitor of osteoclast-mediated bone resorption. It inhibits bone resorption in vitro with an IC₅₀ value of 2 nM. Also acts as a farnesyl diphosphate synthase inhibitor (IC₅₀ = 460 nM) and CD45 protein tyrosine phosphatase inhibitor.

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