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ALDOB, human recombinant

Enzyme that catalyzes the reversible cleavage of fructose 1-phosphate into dihydroxyacetone phosphate and glyceraldehyde
Catalog #: P1157
SKU-Size Size Price Qty
P1157-10 10 μg
$75.00
P1157-50 50 μg
$255.00
More Sizes Get Quote

Product Details

Alternate Name Fructose-bisphosphate aldolase B, ALDB, ALDO2
Gene Symbol ALDOB
Gene ID 229
Source E.coli
Appearance Liquid
Physical Form Description In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 10% glycerol, 0.1 M NaCl
Molecular Weight 42 kDa
Purity by SDS-PAGE > 95%
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSH DSSINQSIGG VILFHETLYQ KDSQGKLFRN ILKEKGIVVG IKLDQGGAPL AGTNKETTIQ GLDGLSERCA QYKKDGVDFG KWRAVLRIAD QCPSSLAIQE NANALARYAS ICQQNGLVPI VEPEVIPDGD HDLEHCQYVT EKVLAAVYKA LNDHHVYLEG TLLKPNMVTA GHACTKKYTP MAHRFP ALTQEQKKEL SEIAQSIVAN G
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Fructose-bisphosphate aldolase B, also known as ALDOB, is one of three known aldolase isoenzymes, and is found in kidney and small adult intestine where it is associated with aldolases A or C. ALDOB catalyzes the reversible cleavage of fructose 1-phosphate into dihydroxyacetone phosphate and glyceraldehyde. It is regulated by the hormones Insulin and glucagon and has been implicated in hereditary fructose intolerance disease. Recombinant human ALDOB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.


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