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Akt/PKB Antibody

based on 2 citations in multiple journalsAkt/PKB Antibody24.1 4
Catalog #: 3247
SKU-Size Size Price Qty
3247-30T 30 µg
3247-100 100 µg
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Product Details

Antibody Target Akt/PKB
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide corresponding to residue surrounding amino acid 80 of human Akt
Accession # P31749
Gene ID 60391226
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation In phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin
Purification Affinity purified
Species Reactivity Human, mouse, rat, bovine
Application Western blot,Immunoprecipitation, Immunohistochemistry
Application & Usage Western blotting (0.5-4 µg/ml), in immunoprecipitation (10-40 µg/ml), and Immunohistochemistry (10-40 µg/ml). However, the optimal conditions should be determined individually. The antibody detects Akt1, Akt2 and Akt3.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Akt, also referred to as PKB and RAC, is the cellular homologue of the viral oncogene v-Akt. This protein kinase is activated by insulin and various growth factors and functions in a pathway involving PI3 kinase as activation is sensitive to wortmanin. Recent evidence sμggests that Akt functions to promote cell survival by actively inhibiting apoptosis.

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Artwohl M et al. (2007) Am. J. Physiol. Endocrinol. Metab. 293: E681-E689.
Saemann, M.D., et al. (2005) J. Clin. Invest. 115: 468-475.
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