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AKR1C3 Inhibitor III

A potent and selective AKR1C3 inhibitor
Catalog #: 2424
SKU-Size Size Price Qty
2424-5 5 mg
2424-25 25 mg
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Product Details

Alternate Name 4-(4-Chlorophenyl)piperazin-1-yl)(morpholino)methanone
Appearance White to off-white solid
Molecular Formula C₁₅H₂₀ClN₃O₂
Molecular Weight 309.79
Purity ≥98% by HPLC
Solubility DMSO
InChi InChI=1S/C15H20ClN3O2/c16-13-1-3-14(4-2-13)17-5-7-18(8-6-17)15(20)19-9-11-21-12-10-19/h1-4H,5-12H2
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


A highly potent and selective inhibitor of the type 5 17-β-hydroxysteroid dehydrogenase AKR1C3 (IC₅₀ = 88 nM). Displays >100-fold selectivity against AKR1C1, AKR1C2 and AKR1C4. Does not display any COX (cyclooxygenase) inhibition at 10 µM in whole blood assay.

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