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Anti-AGTR2 Antibody

Polyclonal Antibody against AGTR2
Catalog #: A1063
$275.00

Product Details

Cat # +Size A1063-50
Size 50 µl
Antibody Target AGTR2
Alternate Name AGTR2 Antibody: AT2, ATGR2, MRX88, Type-2 angiotensin II receptor, Angiotensin II type-2 receptor, AT2
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen 16 amino acid synthetic peptide from near the center of human AGTR2.
Accession # AAS45437
Gene ID 186
Appearance Colourless liquid
Concentration 1 mg/ml
Formulation 50 µg (1mg/ml) of antibody in PBS containing 0.02% sodium azide.
Purification affinity chromatography purified via peptide column.
Species Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA
Positive Control WB, IHC
Application & Usage WB-0.5 μg/mL, IHC-P-5 μg/mL, ELISA,
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

AGTR2 Antibody: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. Like AGTR1, AGTR2 is a seven transmembrane G protein-coupled receptor (GPCR), but AGTR2 does not demonstrate most of the classic features of GPCR signaling. AGTR2 is involved in a wide range of activities, including the induction of neurite outgrowth and the inhibition of cellular proliferation, in addition to the known function of mediation of vasoconstriction.


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