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A potent PARP-1 inhibitor
Catalog #: B2175
SKU-Size Size Price Qty
B2175-5 5 mg
B2175-25 25 mg
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Product Details

Alternate Name 1-(4-((dimethylamino)methyl)phenyl)-8,9-dihydro-2,7,9a-triazabenzo[cd]azulen-6(7H)-one
Appearance Crystalline solid
CAS # 328543-09-5
Molecular Formula C₁₉H₂₀N₄O
Molecular Weight 320.39
Purity ≥98%
Solubility DMSO
InChi InChI=1S/C19H20N4O/c1-22(2)12-13-6-8-14(9-7-13)18-21-16-5-3-4-15-17(16)23(18)11-10-20-19(15)24/h3-9H,10-12H2,1-2H3,(H,20,24)
PubChem CID 9840076
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


AG-14361 is a potent and selective inhibitor of PARP-1 with Ki value of <5 nM in a cell-free assay. AG-14361 sensitizes cells to topoisomerase I poisons by increasing the persistence of DNA strand breaks.

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