Product Details
| abID | ab285682 |
|---|---|
| Alternate Name | Acrp-30, GBP-28, Apm-1, 30 kDa adipocyte complement-related protein, Adipocyte complement-related 30 kDa protein, Adipocyte, C1q and collagen domain-containing protein, Adipose most abundant gene transcript 1 protein, Gelatin-binding protein |
| Gene Symbol | ADIPOQ |
| Gene ID | 9370 |
| Accession # | NP_004788 |
| Source | E. coli |
| Appearance | Lyophilized protein |
| Physical Form Description | Lyophilized powder with no additives |
| Molecular Weight | 30 kDa |
| Purity by SDS-PAGE | ≥90% |
| Endotoxin Level | <0.1 ng/μg |
| Reconstitution Instructions | Recontitute in water containing at least 0.1% BSA to a concentration of 0.1-1.0 mg/ml. This stock solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use. |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -20°C |
| USAGE | For Research Use Only! Not to be used in humans |
Details
Adiponectin (also called Acrp30, AdipoQ) is an adipocyte specific secreted protein that circulates in the plasma. It is induced during adipocyte differentiation and it secretion is stimulated by insulin. Human adiponectin shares about 83% amino acid identity with that of mouse and about 90% with that of rat. Adiponectin plays a role in various physiological processes such as energy homeostasis and obesity. Plasma levels of adiponectin are reduced in obese humans, and decreased levels are associated with insulin resistance and hyperinsulinemia.
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Fei Fang et al., Adiponectin attenuates angiotensin II-induced oxidative stress in renal tubular cells through AMPK and cAMP-Epac signal transduction pathways. Am J Physiol Renal Physiol, Jun 2013; 304: F1366 - F1374.
Hansmann G. et al. (2007) Circulation 115: 1275-1284.
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