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Adenosine kinase, Human Recombinant

Potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides
Catalog #: P1234

In stock

SKU-Size Size Price Qty
P1234-10 10 μg
$105.00
P1234-50 50 μg
$315.00

Product Details

Alternate Name ADK, AK
Gene Symbol ADK
Gene ID 132
Accession # P55263
Source E.coli
Appearance Liquid
Physical Form Description In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 20% glycerol, 1 mM EDTA, 50 mM NaCl
Molecular Weight 40.5 kDa
Purity by SDS-PAGE > 95%
Biological Activity Specific activity > 30 pmol/min/ug
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MRENILFGMG NPLLDISAVV DKDFLDKYSL KPNDQILAED KHKELFDELV KKFKVEYHAG GSTQNSIKVA QWMIQQPHKA ATFFGCIGID KFGEILKRKA AEAHVDAHYY EQNEQPTGTC AACITGDNRS LIANLAAANC YKKEKHLDLE KNWMLVEKAR VCYIAGFFLT VSPESVLKVA HHASENNRIF TLNLSAPFIS QFYKESLMKV MP
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Adenosine kinase, also known as ADK is an abundant enzyme in mammalian tissues that catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine kinase has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Recombinant human Adenosine kinase, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.


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