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A potent and selective Wnt pathway inhibitor
Catalog #: B2437
SKU-Size Size Price Qty
B2437-1 1 mg
B2437-5 5 mg
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Product Details

Alternate Name SM04690, N-(5-{3-[7-(3-fluorophenyl)-1H-imidazo[4,5-c]pyridin-2-yl]-1H-indazol-5-yl}pyridin-3-yl)-3-methylbutanamide
Appearance Crystalline solid
CAS # 1467093-03-3
Molecular Formula C₂₉H₂₄FN₇O
Molecular Weight 505.56
Purity ≥98% by HPLC
Solubility >20 mg/ml in DMSO
InChi InChI=1S/C29H24FN7O/c1-16(2)8-26(38)33-21-10-19(12-31-13-21)17-6-7-24-22(11-17)28(37-36-24)29-34-25-15-32-14-23 (27(25)35-29)18-4-3-5-20(30)9-18/h3-7,9-16H,8H2,1-2H3,(H,33,38)(H,34,35)(H,36,37)
PubChem CID 135565709
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Adavivint is a potent and selective Wnt pathway inhibitor with an EC₅₀ of 3 nM in vitro; induces hMSC differentiation into mature, functional chondrocytes and decreases cartilage catabolic marker levels.

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