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A p210bcr/abl kinase inhibitor
Catalog #: B2787
SKU-Size Size Price Qty
B2787-5 5 mg
B2787-25 25 mg
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Product Details

Alternate Name AG 957 Adamantyl Ester; 4-[[(2,5-Dihydroxyphenyl)methyl]amino]benzoic acid tricyclo[,7]dec-1-yl ester; NSC-680410
Peptide Sequence N/A
Appearance Off-white solid
CAS # 241127-58-2
Molecular Formula C₂₄H₂₇NO₄
Molecular Weight 393.48
Purity ≥98% by HPLC
Solubility >30 mg/ml Ethanol, >30 mg/ml DMSO
InChi InChI=1S/C24H27NO4/c26-21-5-6-22(27)19(10-21)14-25-20-3-1-18(2-4-20)23(28)29-24-11-15-7-16(12-24)9-17(8-15)13-24/h1-6,10,15-17,25-27H,7-9,11-14H2
PubChem CID 387042
MDL Number MFCD06411386
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Adaphostin is a p210bcr/abl tyrosine kinase inhibitor (IC50 = 14 μM) that displays anti-proliferative activity in leukemia models, human prostate cancer cell line PC-3 and other cancer cell lines. Adaphostin is a potent inducer of myeloid cell death.

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