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ACTL6A Antibody

Polyclonal Antibody to detect ACTL6A in human, mouse and rat samples
Catalog #: 6284
SKU-Size Size Price Qty
6284-30T 30 µg
$89.00
6284-100 100 µg
$275.00
More Sizes Get Quote

Product Details

Antibody Target ActL6A
Alternate Name 53 kDa BRG1-associated factor A, Actin-related protein Baf53a, ArpNbeta, BRG1-associated factor 53A
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide at N-terminal
Accession # O96019
Gene ID 86
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 µg (0.5 mg/ml) of antibody in PBS, 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol, pH 7.2
Purification Affinity purified
Species Reactivity Human, mouse, rat
Application Western blot
Positive Control Western blot: 3T3 cell lysate
Application & Usage Western blot: 1:200
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Actin-like protein 6A is a protein that in humans is encoded by the ACTL6A gene. This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix.


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