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Activin A, mouse recombinant

A protein complex enhancing FSH biosynthesis and secretion
Catalog #: 4725
SKU-Size Size Price Qty
4725-10 10 μg
$255.00
4725-100 100 μg
$1,085.00
4725-1000 1 mg
$7,645.00
More Sizes Get Quote

Product Details

Alternate Name Inhibin beta-1, FRP, FSH-releasing protein
Gene Symbol INHBA
Gene ID 3624
Accession # P08476
Source E. coli
Appearance Lyophilized protein
Physical Form Description Recombinant mouse Activin A is lyophilized with 0.02% TFA.
Molecular Weight 26.2 kDa
Purity by SDS-PAGE ≥95%
Purity by ≥95%
Endotoxin Level <0.1 EU/μg purified protein
Biological Activity The activity is determined by the ability to induce cytoxicity of MPC-11 cells and is typically less than 2 ng/mL.
Reconstitution Instructions Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water, which can
Amino Acid Sequence MGLECDGKVN ICCKKQFFVS FKDIGWNDWI IAPSGYHANY CEGECPSHIA GTSGSSLSFH STVINHYRMR GHSPFANLKS CCVPTKLRPM SMLYYDDGQN IIKKDIQNMI VEECGCS
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Activin A is a member of the TGFbeta family of proteins produced by many cell types throughout development. Activins interact with Type I and Type II serine/threonine kinases to signal to SMAD proteins to regulate a variety of functions, including cell proliferation, differentiation, wound healing, apoptosis, metabolism, etc. Activin A is a homodimer of two beta A chains and is not biologically active until the N terminal propeptide is cleaved from each. Mouse Activin A has 100% amino acid sequence identity to human, rat, porcine, bovine and feline proteins. Recombinant mouse Activin A is a nonglycosylated homodimer, containing two 117 amino acid chains, with a total molecular weight of 26.2 kDa


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