Product Details
| Alternate Name | SLAM Family Member 6; NTB-A; KALI; CD352 |
|---|---|
| Gene ID | 114836 |
| Accession # | Q96DU3 |
| Source | Human plasma |
| Appearance | Lyophilized protein |
| Physical Form Description | Lyophilized powder |
| Molecular Weight | 23.4 kDa (predicted); 30-50 kDa (observed) |
| Purity by SDS-PAGE | > 95% |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4 |
| Endotoxin Level | < 1.0 EU per μg as determined by the LAL method. |
| Biological Activity | Measured by its ability to induce IFN-γ secretion by PBMC cells |
| Amino Acid Sequence | Leu 28 to Lys 225 with C-terminal His Tag |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -20ºC |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
SLAMF6 (also known as Ly108) is a transmembrane protein expressed on natural killer (NK), T-, and B-lymphocytes. SLAMF6 undergoes tyrosine phosphorylation and associates with SH2 domain-containing proteins to function as a coreceptor in NK cell activation. SLAMF6 also has functions in T-cell differentiation and in the humoral immune response.
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