Active SLAMF6/Ly108, Human Recombinant

Key protein in the activation and regulation of natural killer cells
Catalog #: P1738 | abID:

Product Details

Alternate Name SLAM Family Member 6; NTB-A; KALI; CD352
Gene ID 114836
Accession # Q96DU3
Source Human plasma
Appearance Lyophilized protein
Physical Form Description Lyophilized powder
Molecular Weight 23.4 kDa (predicted); 30-50 kDa (observed)
Purity by SDS-PAGE > 95%
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4
Endotoxin Level < 1.0 EU per μg as determined by the LAL method.
Biological Activity Measured by its ability to induce IFN-γ secretion by PBMC cells
Amino Acid Sequence Leu 28 to Lys 225 with C-terminal His Tag
Handling Centrifuge the vial prior to opening.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


SLAMF6 (also known as Ly108) is a transmembrane protein expressed on natural killer (NK), T-, and B-lymphocytes. SLAMF6 undergoes tyrosine phosphorylation and associates with SH2 domain-containing proteins to function as a coreceptor in NK cell activation. SLAMF6 also has functions in T-cell differentiation and in the humoral immune response.

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