Active Recombinant Human CAXII Protein

Overexpressed in renal carcinomas
Catalog #: P1704 | abID: ab201875

Product Details

abID ab201875
Alternate Name Carbonic anhydrase 12 isoform 1, CAXII, HsT18816, CA12, FLJ20151, Carbonate dehydratase XII, carbonic anhydrase XII, CA-XII, Tumor antigen HOM-RCC-3.1.3
Gene ID 771
Accession # O43570
Source Baculovirus
Appearance Liquid
Physical Form Description Liquid
Molecular Weight 31.94 kDa
Purity by SDS-PAGE ≥ 90%
Endotoxin Level < 1 EU per 1 µg of protein as determined by LAL method
Amino Acid Sequence The target is expressed with the sequence (aa 25-301) of Human CAXII with a His-tag at the C-terminus.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


CA12, also known as Carbonic anhydrase 12, is an enzyme that in humans is encoded by the CA12 gene. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas.

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