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Product Details
| Alternate Name | Beta-secretase 1, Aspartyl protease 2, ASP2, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, Memapsin-2, Membrane-associated aspartic protease 2, Aspartic-like protease 56 kDa, Aspartyl protease 1, Beta-site amyloid |
|---|---|
| Gene Symbol | BACE1 |
| Gene ID | 23621 |
| Accession # | P56817 |
| Source | Insect cell |
| Appearance | Liquid |
| Physical Form Description | Supplied in PBS with 50% glycerol |
| Molecular Weight | 47 kDa |
| Purity by SDS-PAGE | ≥90% |
| Biological Activity | BioVision’s recombinant human beta-Secretase/BACE-1 is biologically active as determined by using the β-Secretase Activity Assay Kit (Cat# K360-100). |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -70°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not to be used in humans |
Details
β-Secretase, also called BACE1 (β-site of APP cleaving enzyme) or memapsin-2 is an aspartic-acid protease important in the pathogenesis of Alzheimer's disease, and in the formation of myelin sheaths in peripheral nerve cells. The transmembrane protein, contains two active site aspartate residues in its extracellular protein domain and may function as a dimer..
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