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Active NGFB, Murine Recombinant

Critical for development and maintenance of sympathetic and sensory nervous systems
Catalog #: P1758
SKU-Size Size Price Qty
P1758-10 10 µg
$195.00
P1758-50 50 µg
$295.00
More Sizes Get Quote

Product Details

Alternate Name Beta-NGF; NGF; Beta nerve growth factor
Gene ID 18049
Accession # P01139
Source E. coli
Appearance Lyophilized protein
Physical Form Description Lyophilized powder
Molecular Weight 12.4 kDa
Purity by SDS-PAGE > 95%
Formulation Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,200 mM NaCl,pH 8.0
Endotoxin Level < 1.0 EU per µg as determined by the LAL method
Amino Acid Sequence Met 130 to Arg 239
Specific Activity Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is 0.5-1.5 ng/ml
Handling Centrifuge the vial prior to opening.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The beta nerve growth factor (NGFB) is important for the development and maintenance of the sympathetic and sensory nervous system. NGFB is a ligand for the NTRK1 and HGFR receptors, and binding to these receptors activates cellular signaling cascades to regulate neuronal proliferation, differentiation, and survival.


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