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Product Details
| Alternate Name | Beta-NGF; NGF; Beta nerve growth factor |
|---|---|
| Gene ID | 18049 |
| Accession # | P01139 |
| Source | E. coli |
| Appearance | Lyophilized protein |
| Physical Form Description | Lyophilized powder |
| Molecular Weight | 12.4 kDa |
| Purity by SDS-PAGE | > 95% |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,200 mM NaCl,pH 8.0 |
| Endotoxin Level | < 1.0 EU per µg as determined by the LAL method |
| Amino Acid Sequence | Met 130 to Arg 239 |
| Specific Activity | Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is 0.5-1.5 ng/ml |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -20ºC |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
The beta nerve growth factor (NGFB) is important for the development and maintenance of the sympathetic and sensory nervous system. NGFB is a ligand for the NTRK1 and HGFR receptors, and binding to these receptors activates cellular signaling cascades to regulate neuronal proliferation, differentiation, and survival.
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