Active LAMP2/CD107b, Human Recombinant

Plays a role in lysosomal protein degradation
Catalog #: P1740 | abID:

Product Details

Alternate Name Lysosomal Associated Membrane Protein 2; Lysosome-Associated Membrane Glycoprotein 2; CD107 Antigen-Like Family Member B; LAMP-2; LGP-96; LGP110; LAMPB; DND
Gene ID 3920
Accession # P13473
Source Human cells
Appearance Lyophilized protein
Molecular Weight 33.9 kDa (predicted); 78 kDa (observed)
Purity by SDS-PAGE > 95%
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Endotoxin Level < 1.0 EU per μg as determined by the LAL method.
Biological Activity Immobilized human Galectin-3 (at 1.5 μg/ml, 100 μl/well) can bind Active LAMP2/CD107b with an ED50 of 12.73 μg/ml
Amino Acid Sequence Leu 29 to Ile 375 with C-terminal 6xHis Tag
Handling Centrifuge the vial prior to opening.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


LAMP2 (CD107b) is a membrane glycoprotein that functions in the protection, maintenance, and adhesion of the lysosome. LAMP2 plays an important role in chaperone-mediated autophagy to mediate lysosomal degradation of proteins in response to stress. LAMP2 may also have a role in tumor cell metastasis.

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