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Active HRV14 3C Protease Recombinant

≥90% Pure Active Recombinant HRV14 3C Protease for inhibitor screening assays, activity studies, selectivity profiling, western blotting, ELISA, and numerous such applications.
Catalog #: 8012
SKU-Size Size Price Qty
8012-20 20 µg
$145.00
8012-100 100 µg
$495.00
More Sizes Get Quote

Product Details

Alternate Name Precission protease, 3C Protease
Gene Symbol HRV14
Gene ID 1461213
Accession # P03303
Source E. coli
Appearance Liquid
Physical Form Description 1 mg/ml in 50 mM Tris, 100 mM NaCl, 5 mM DTT, pH 8.0 containing 20% glycerol
Molecular Weight 20 kDa (1538-1719 aa).
Purity by SDS-PAGE ≥ 90%
Biological Activity BioVision’s Active HRV14 3C Protease has been tested for its activity using HRV 3C Protease Activity Assay Kit (Colorimetric) (K214-100).
Amino Acid Sequence 1538-1719 aa
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans

Details

Human rhinovirus (HRV) infections are the most frequent causative agents of common cold and various other upper respiratory tract infections. Rhinoviruses are members of the picornavirus family, which have a positive-sense, single-stranded RNA genome that is translated into a single polyprotein precursor. In the case of HRVs, the viral polyprotein is mainly processed by the proteases (2A and 3C) to generate functional proteins and enzymes. BioVision’s active HRV14 3C Protease is a recombinant form of the 3C protease from human rhinovirus type 14. The enzyme is highly pure with selective and high site-specific cleavage activity for Precission cleavage site (Leu-Glu-Val-Leu-Phe-Gln/Gly-Pro), thereby allowing for the production of recombinant proteins with minimal number of extra amino acids. HRV14 3C Protease also has therapeutic implications as a potential target for the development of antiviral agents.


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