Active EphB2 (Fc Tag), Human Recombinant

Involved in axon guidance during development
Catalog #: P1741 | abID:

Product Details

Alternate Name EPH Receptor B2; Developmentally-Regulated Eph-Related Tyrosine Kinase; Tyrosine-Protein Kinase Receptor EPH-3; Tyrosine-Protein Kinase TYRO5
Gene ID 2048
Accession # P29323
Source Human cells
Appearance Lyophilized protein
Physical Form Description Lyophilized powder
Molecular Weight 78.5 kDa (predicted); 120 kDa (observed)
Purity by SDS-PAGE > 90%
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Endotoxin Level < 1.0 EU per μg as determined by the LAL method.
Biological Activity Immobilized Active EphB2 (Fc Tag) 2 μg/ml (100 μl/well) can bind Ephrin B2
Amino Acid Sequence Val 19 to Ser 482 with C-terminal Fc Tag
Handling Centrifuge the vial prior to opening.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Ephrin Type-B Receptor 2 (EphB2) is a transmembrane receptor tyrosine kinase glycoprotein that functions through bidirectional signaling between adjacent cells. EphB2 functions in axon guidance during development, and also regulates development of dendrites and formation of synapses. EphB2 also controls angiogenesis, movement and adhesion of certain cells, and may function as a tumor suppressor. Some mutations of EphB2 have been associated with prostate and brain cancer.

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