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ACTB-1003

A potent kinase inhibitor
Catalog #: B2016

In stock

SKU-Size Size Price Qty
B2016-5 5 mg
$175.00
B2016-25 25 mg
$695.00
More Sizes Get Quote

Product Details

Alternate Name 1-(4-(4-amino-6-(methoxymethyl)-7-(morpholinomethyl)pyrrolo[2,1-f][1,2,4]triazin-5-yl)-2-fluorophenyl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)urea
Appearance Crystalline solid
CAS # 939805-30-8
Molecular Formula C₂₇H₂₆F₅N₇O₃
Molecular Weight 591.53
Purity ≥98%
Solubility DMSO
SMILES OCC1=C(N2C(=C1C3=CC(=C(C=C3)NC(=O)NC4=C(C=CC(=C4)C(F)(F)F)F)F)C(=NC=N2)N)CN5CCOCC5
InChi InChI=1S/C27H26F5N7O3/c1-41-13-17-22(12-38-6-8-42-9-7-38)39-24(25(33)34-14-35-39)23(17)15-2-5-20(19(29)10-15)36-26(40)37-21-11-16(27(30,31)32)3-4-18(21)28/h2-5,10-11,14H,6-9,12-13H2,1H3,(H2,33,34,35)(H2,36,37,40)
InChi Key GZPJCJKUZPUFAL-UHFFFAOYSA-N
PubChem CID 23653175
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

ACTB-1003 is a potent kinase inhibitor with IC₅₀s of 6, 2 and 4 nM for FGFR1, VEGFR2 and Tie-2, respectively. Displays anticancer activities.


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