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ACT-129968

Apotent and selective CRTh2 antagonist
Catalog #: B2316

In stock

SKU-Size Size Price Qty
B2316-10 10 mg
$85.00
B2316-50 50 mg
$335.00
More Sizes Get Quote

Product Details

Alternate Name Setipiprant,2-(2-(1-naphthoyl)-8-fluoro-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)acetic acid
Appearance Crystalline solid
CAS # 866460-33-5
Molecular Formula C₂₄H₁₉FN₂O₃
Molecular Weight 402.43
Purity ≥98% by HPLC
Solubility >30 mg/ml (DMSO)
SMILES C1CN(CC2=C1N(C3=C2C=C(C=C3)F)CC(=O)O)C(=O)C4=CC=CC5=CC=CC=C54
InChi InChI=1S/C24H19FN2O3/c25-16-8-9-21-19(12-16)20-13-26(11-10-22(20)27(21)14-23(28)29)24(30)18-7-3-5-15-4-1-2-6-17(15)18/h1-9,12H,10-11,13-14H2,(H,28,29)
InChi Key IHAXLPDVOWLUOS-UHFFFAOYSA-N
PubChem CID 49843471
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A potent and selective CRTh2 antagonist. CRTh2 is a G-protein-coupled receptor for prostaglandin D2 (PGD2), a key mediator in inflammatory disorders.


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