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Aclidinium bromide

A long-acting reversible antagonist at the muscarinic acetylcholine receptors (mAChRs)
Catalog #: B2281

In stock

SKU-Size Size Price Qty
B2281-10 10 mg
$65.00
B2281-50 50 mg
$225.00
More Sizes Get Quote

Product Details

Alternate Name (3R)-3-[(2-hydroxy-2,2-di-2-thienylacetyl)oxy]-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane, monobromide; LAS34273; LAS W-330
Appearance Off-white solid
CAS # 320345-99-1
Molecular Formula C₂₆H₃₀NO₄S₂• Br
Molecular Weight 564.6
Purity ≥98% by HPLC
Solubility DMSO (~15 mg/ml)
SMILES C1C[N+]2(CCC1C(C2)OC(=O)C(C3=CC=CS3)(C4=CC=CS4)O)CCCOC5=CC=CC=C5.[Br-]
InChi InChI=1S/C26H30NO4S2.BrH/c28-25(26(29,23-9-4-17-32-23)24-10-5-18-33-24)31-22-19-27(14-11-20(22)12-15-27)13-6-16-30-21-7-2-1-3-8-21;/h1-5,7-10,17-18,20,22,29H,6,11-16,19H2;1H/q+1;/p-1/t20?,22-,27?;/m0./s1
InChi Key XLAKJQPTOJHYDR-QTQXQZBYSA-M
PubChem CID 11519741
MDL Number MFCD09954105
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Aclidinium bromide is a long-acting reversible antagonist at the muscarinic acetylcholine receptors (mAChRs), M1, M2, M3, M4, and M5 (Kis= 0.1, 0.14, 0.14, 0.21, and 0.16 nM, respectively). Useful for the treatment of chronic obstructive pulmonary disease


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