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Product Details
| Alternate Name | N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]-acetamide L-579,486 NSC 145177 |
|---|---|
| Appearance | White solid |
| CAS # | 59-66-5 |
| Molecular Formula | C₄H₆N₄O₃S₂ |
| Molecular Weight | 222.25 |
| Purity | ≥98% |
| Solubility | >20 mg/ml DMSO |
| SMILES | CC(=O)NC1=NN=C(S1)S(=O)(=O)N |
| InChi | InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) |
| InChi Key | BZKPWHYZMXOIDC-UHFFFAOYSA-N |
| PubChem CID | 1986 |
| MDL Number | MFCD00003105 |
| Handling | Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure. |
| Storage Conditions | -20ºC |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Acetazolamide is a potent carbonic anhydrase (CA) inhibitor. It is currently used as an antiglaucoma, antiepileptic and diuretic agent, and is also effective in the treatment of Idiopathic intracranial hypertension (IIH). Modulates epileptiform synchronization in rat brain slices. Increases speed of synaptic vesicle recycling and changes synaptic performance in ex vivo murine neuromuscular junction.
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