Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

New

ACE1 Colorimetric Activity Assay Kit

to detect ACE1 activity in a variety of samples
Catalog #: K2001
$465.00

Product Details

Cat # +Size K2001-100
Size 100 assays
Kit Summary BioVision’s ACE1 Activity Assay Kit can be used to detect its activity in biological samples. This kit utilizes the ability of an active ACE1 to hydrolyze a synthetic substrate, which results in the decrease in optical density at 345 nm. The assay kit provides a rapid, simple and sensitive method to detect ACE1 activity as low as 40 mU in a variety of samples.
Detection Method Absorbance, OD 345 nm
Species Reactivity All
Applications Measurement of ACE1 activity in Plasma or Serum samples
Features & Benefits • Simple
• Rapid
• Sensitive method to detect ACE1 activity as low as 40 mU in a variety of samples
Kit Components • ACE1 Substrate
• ACE1 Assay Buffer
• ACE1 Enzyme
• 96-Well Clear Bottom UV Plate
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Angiotensin-I-converting enzyme (ACE1) is a peptidyl dipeptidase that catalyzes the conversion of decapeptide angiotensin I to octapeptide angiotensin II, by removing a carboxy-terminal dipeptide. ACE is a key part of the renin angiotensin system (RAS) that regulates blood pressure. Increased ACE activity leads to an increase in the angiotensin II (Ang II) levels. This may increase the risk of developing neurodegenerative diseases including Parkinson, Alzheimer, Huntington, Multiple Sclerosis etc. Elevated levels of Ang II mediate cardiac remodeling (cardiac hypertrophy and fibrosis), which is a hallmark in heart failure. Previous researchers have shown that ACE activity is a better predictor of pathologies associated with Type 2 diabetes than ACE levels in serum samples. BioVision’s ACE1 Activity Assay Kit can be used to detect its activity in biological samples. This kit utilizes the ability of an active ACE1 to hydrolyze a synthetic substrate, which results in the decrease in optical density at 345 nm. The assay kit provides a rapid, simple and sensitive method to detect ACE1 activity as low as 40 mU in a variety of samples.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.