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Acarbose

An inhibitor of α-glucosidase and a antidiabetic agent
Catalog #: B2104

In stock

SKU-Size Size Price Qty
B2104-100 100 mg
$65.00
B2104-500 500 mg
$175.00
More Sizes Get Quote

Product Details

Alternate Name O-4,6-dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1→4)-O-α-D-glucopyranosyl-(1→4)-D-glucose; BAY-g 5421
Appearance White to off-white solid
CAS # 56180-94-0
Molecular Formula C₂₅H₄₃NO₁₈
Molecular Weight 645.6
Purity ≥98%
Solubility H₂O (50 mg/ml)
SMILES CC1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)NC4C=C(C(C(C4O)O)O)CO
InChi InChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23?,24-,25-/m1/s1
InChi Key XUFXOAAUWZOOIT-UGEKTDRHSA-N
PubChem CID 41774
MDL Number MFCD00869592
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Acarbose is an inhibitor of α-glucosidase and pancreatic α-amylase with antihyperglycemic activity. Acarbose binds to and inhibits α-glucosidase, an enteric enzyme found in the brush border of the small intestines that hydrolyzes oligosaccharides and disaccharides into glucose and other monosaccharides. Acarbose has been used to inhibit postprandial hyperglycemia associated with diabetes without cardiovascular complications.


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