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AC710

A potent PDGFR-family kinases inhibitor
Catalog #: 2884
SKU-Size Size Price Qty
2884-5 5 mg
$145.00
2884-25 25 mg
$575.00
More Sizes Get Quote

Product Details

Alternate Name N-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-5-((1-ethyl-2,2,6,6-tetramethylpiperidin-4-yl)oxy)picolinamide
Appearance Crystalline solid
CAS # 1351522-04-7
Molecular Formula C₃₁H₄₂N₆O₄
Molecular Weight 562.7
Purity ≥98% by HPLC
Solubility DMSO
SMILES CCN1C(CC(CC1(C)C)OC2=CN=C(C=C2)C(=O)NC3=CC=C(C=C3)NC(=O)NC4=NOC(=C4)C(C)(C)C)(C)C
InChi InChI=1S/C31H42N6O4/c1-9-37-30(5,6)17-23(18-31(37,7)8)40-22-14-15-24(32-19-22)27(38)33-20-10-12-21(13-11-20)34-28(39)35-26-16-25(41-36-26)29(2,3)4/h10-16,19,23H,9,17-18H2,1-8H3,(H,33,38)(H2,34,35,36,39)
InChi Key JVCWPUFNLFSKFS-UHFFFAOYSA-N
PubChem CID 54760053
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

AC710 is a potent, and selective PDGFR-family kinases inhibitor with Kd values of 0.6 nM,1.0 nM, 1.3 nM and 1.0 nM for FLT3, KIT, PDGFRα and PDGFRβ respectively. Displays potent anticancer activity.


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