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Ac-VEID-pNA

A caspase-6 substrate
Catalog #: B2283

In stock

SKU-Size Size Price Qty
B2283-5 5 mg
$125.00
B2283-25 25 mg
$495.00
More Sizes Get Quote

Product Details

Alternate Name Caspase-6 substrate (chromogenic), N-Acetyl-Val-Glu-Ile-Asp-p-nitroanilide
Peptide Sequence Ac-Val-Glu-Ile-Asp-pNA
Appearance White to off-white solid
CAS # 189684-54-6
Molecular Formula C₂₈H₄₀N₆O₁₁
Molecular Weight 636.65
Purity ≥98% by HPLC
Solubility DMSO (>10 mg/ml)
SMILES CCC(C)C(C(=O)NC(CC(=O)O)C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)C(CCC(=O)O)NC(=O)C(C(C)C)NC(=O)C
InChi InChI=1S/C28H40N6O11/c1-6-15(4)24(33-25(40)19(11-12-21(36)37)31-27(42)23(14(2)3)29-16(5)35)28(43)32-20(13-22(38)39)26(41)30-17-7-9-18(10-8-17)34(44)45/h7-10,14-15,19-20,23-24H,6,11-13H2,1-5H3,(H,29,35)(H,30,41)(H,31,42)(H,32,43)(H,33,40)(H,36,37)(H,38,39)/t15-,19-,20-,23-,24-/m0/s1
InChi Key VXTVKOWKXXPPNE-PZQVQNRFSA-N
PubChem CID 25108783
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Ac-VEID-pNA, is a colorimetric substrate for caspase-6 and related cysteine proteases. Cleavage of the substrate by a caspase results in the release of pNA, which can be detected by its absorbance at 405nm (ε=10,500 M-1cm-1).


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