Ac-IEPD-AFC (ab289850)
Key features and details
- Fluorescent Granzyme B substrate
- CAS Number: 1135417-31-0
- Purity: >= 95%
>14 mg/ml in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Ac-IEPD-AFC -
Description
Fluorescent Granzyme B substrate -
Alternative names
- Ac-Ile-Glu-Pro-Asp-AFC
- N-Acetyl-Ile-Glu-Pro-Asp-(7-amino-4-trifluoromethylcoumarin)
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Biological description
Fluoregenic Granzyme B substrate. Granzyme B activity can be quantified by fluorescent detection of free AFC that has an excitation maximum at 400 nm and emission maximum at 505 nm.
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Purity
>= 95% -
CAS Number
1135417-31-0
Properties
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Chemical name
(4S)-4-[[(2S,3S)-2-acetamido-3-methylpentanoyl]amino]-5-[(2S)-2-[[(2S)-3-carboxy-1-oxo-1-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]propan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-oxopentanoic acid
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Molecular weight
725.70 -
Molecular formula
C32H38F3N5O11 -
PubChem identifier
25108575 -
Storage instructions
Shipped at 4°C. Store at -20°C. Store In the Dark. Store under desiccating conditions. -
Solubility overview
>14 mg/ml in DMSO
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SMILES
CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)N1CCCC1C(=O)NC(CC(=O)O)C(=O)NC2=CC3=C(C=C2)C(=CC(=O)O3)C(F)(F)F)NC(=O)C -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab289850 has not yet been referenced specifically in any publications.