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A1 Antibody

based on 1 citations in multiple journalsA1 Antibody14.1 4
Catalog #: 3401
SKU-Size Size Price Qty
3401-30T 30 µg
$89.00
3401-100 100 µg
$255.00
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Product Details

Antibody Target Bcl-2-related protein A1
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide surrounding amino acid 37 of human A1
Accession # Q16548
Gene ID 597
Appearance Colorless liquid
Concentration 0.2 mg/ml
Formulation 100 µg (0.2 mg/ml) protein A purified rabbit anti-A1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification Affinity purified
Species Reactivity Human, mouse, rat
Application Western blot
Application & Usage Western blotting (0.5-4 µg/ml), immunoprecipitation, and Immunohistochemistry. However, the optimal conditions should be determined individually. The A1 antibody detects A1 (Bfl-1) of human, mouse, and rat origins.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A1 (also designated Bfl-1) is a Bcl-2 family protein that dimerizes with both Bcl-2 and Bax, and has been identified as a hematopoietic-specific, early inducible gene. Althoμgh A1 demonstrated properties similar to those of Bcl-2, its function may be more temporally regulated during myeloid differentiation and is dependent on additional growth stimuli to confer its life promoting properties. A1 is abundantly expressed in bone marrow and at low levels in other tissues. A1 expression has been correlated to stomach cancer.


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Talen S. et al. (2006) J. Clin. Endocrinol. Metab. 91: 1042-1047.
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