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A Na(v1.8) blocker
Catalog #: 2559
SKU-Size Size Price Qty
2559-5 5 mg
2559-25 25 mg
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Product Details

Alternate Name 5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide
Appearance Off-white solid
CAS # 944261-74-9
Molecular Formula C₁₉H₁₆ClNO₄
Molecular Weight 357.8
Purity ≥98% by TLC
Solubility DMSO (~30 mg/ml) or EtOH (~ 5 mg/ml)
InChi InChI=1S/C19H16ClNO4/c1-23-15-9-14(10-16(11-15)24-2)21-19(22)18-8-7-17(25-18)12-3-5-13(20)6-4-12/h3-11H,1-2H3,(H,21,22)
PubChem CID 16038374
MDL Number MFCD10574689
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


A-803467 is a potent, selective inhibitor of the TTX-resistant voltage-gated sodium channel Na(v1.8). Na(v1.8) is preferentially expressed in sensory neurons, and inhibition attenuates both inflammatory and neuropathic pain in a variety of animal models. IC50's for rat and human Na(v1.8) are 140 nM and 8.0 nM respectively.

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