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A-769662

A potent AMPK activator
Catalog #: 1719

In stock

$255.00

Product Details

Cat # +Size 1719-5
Size 5 mg
Alternate Name 4-Hydroxy-3-(2’-hydroxy-[1,1’-biphenyl]-4-yl-)-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carbonitrile
Appearance Crystalline solid
CAS # 844499-71-4
Molecular Formula C₂₀H₁₂N₂O₃S
Molecular Weight 360.39
Purity ≥98% by HPLC
Solubility DMSO(30 mg/ml) or Ethanol (5 mg/ml)
SMILES C1=CC=C(C(=C1)C2=CC=C(C=C2)C3=CSC4=C3C(=C(C(=O)N4)C#N)O)O
InChi InChI=1S/C20H12N2O3S/c21-9-14-18(24)17-15(10-26-20(17)22-19(14)25)12-7-5-11(6-8-12)13-3-1-2-4-16(13)23/h1-8,10,23H,(H2,22,24,25)
InChi Key CTESJDQKVOEUOY-UHFFFAOYSA-N
PubChem CID 54708532
MDL Number MFCD11977269
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Cell-permeable. A potent AMPK activator. Directly stimulates partially purified rat liver AMPK (EC₅₀ = 0.8 µM) and inhibits fatty acid synthesis in primary rat hepatocytes (IC5₅₀ = 3.2 µM).


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