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Product Details
| Alternate Name | 8- Bromoadenosine- 3', 5'- cyclic monophosphate; cyclic 8- bromoadenosine- 3', 5'- monophosphate; 8- bromoadenosine- 3', 5'-Monophosphate |
|---|---|
| Appearance | White to off-white solid |
| CAS # | 76939-46-3 |
| Molecular Formula | C₁₀H₁₀BrN₅O₆P. Na |
| Molecular Weight | 430.08 |
| Purity | ≥98% by TLC |
| Solubility | H₂O (~100 mg/ml) |
| SMILES | C1C2C(C(C(O2)N3C4=C(C(=NC=N4)N)N=C3Br)O)OP(=O)(O1)[O-].[Na+] |
| InChi | InChI=1S/C10H11BrN5O6P.Na/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-5(17)6-3(21-9)1-20-23(18,19)22-6;/h2-3,5-6,9,17H,1H2,(H,18,19)(H2,12,13,14);/q;+1/p-1 |
| InChi Key | DMRMZQATXPQOTP-UHFFFAOYSA-M |
| PubChem CID | 23712387 |
| MDL Number | MFCD00005844 |
| Handling | Protect from moisture and light |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
A cell-permeable cAMP analog that is more resistant to hydrolysis by phosphodiesterases than cAMP. Activates protein kinase A, inhibits growth, decreases proliferation, increases differentiation, and induces apoptosis of cultured cells. Also recently shown to improve the reprogramming efficiency of human neonatal foreskin fibroblast (HFF1) cells 2-fold.
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